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OECD 442C: Direct peptide reactivity assay (DPRA) for skin sensitization
Genetic, Acute, In Vitro Alternate
OECD 442C: Direct peptide reactivity assay (DPRA) for skin sensitization
Record Type:Study
直接肽反应试验(DPRA)了ctively used to test the sensitivity potential of a chemical as a human health hazard on the skin.
The test, adopted by the OECD and the EU, measures the reactivity of a test compound with model synthetic peptides containing either lysine or cysteine. The assay is used to test between skin sensitizers and non-sensitizers.
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