.png){kind=icon}
神经兽性评估（NHP模型研究）
神经兽性电池评估测试新生儿NHP的群体，评估肌肉色调，环境响应能力，年龄适当的反射和行为模式，以及反应的活力。电池评估自主神经系统的功能。
The complete neurobehavioral assessment is designed to be safe for both NHPs and the technicians conducting the assessments, examinging both autonomic and central and nervous system functions, which are easily discriminated. Respiration rate, muzzle color and initial state are first recorded by observing the undisturbed model in an incubator. Both observed and elicited muscle tonus are recorded.
Additional evaluations of muscle tone include wrist and ankle dorsiflexion, tested by turning the hand/foot palm side up on the surface and noting how rapidly it returns to the initial position. Palmer grasp reflex, righting reflex and clasp-grasp reflex are involuntary reflexes in the neonatal NHP and are tested. A series of reflexes in the face area are tested. To elicit visual following an object is held in front of the model's face at the midline and then moved to the left and right and is scored.
Lipsmack orient is a species-typical response that is involuntary at birth. Three feeding-related reflexes including sucking, rooting and snout reflex are scored.T he pupil response to light, nystagmus response to rotation, and eyelid blink in response to glabellar tap are also scored. The final reflex tested is the Moro reflex, which is a model's response to loss of support.
About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC.了解有关我们对更换，重新塑造和炼制非临床研究模式的承诺。