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T细胞依赖性抗体反应测定
Immunotoxicology, Antibodies
Hybridoma development
Hybridoma development involves the generation of cell lines that produce large numbers of a specific monoclonal antibody (mAb). The process involves immunization of an animal, usually a mouse, with a specific antigen to initiate an immune response and allow isolation of antibody-producing B cells. These are then fused with immortal myeloma cells to generate the hybridomas. The hybridomas are then screened, selected and the monoclonal population expanded. Hybridomas have a wide range of in vivo applications.
About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC.了解有关我们对更换，重新塑造和炼制非临床研究模式的承诺。