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Inhalation Toxicology
通过意外吸入暴露于化学物质对人类健康存在潜在的风险，包括工人安全。曝光可能会造成急性风险或导致这些毒物的延长术语，特别是对于呼吸系统。其他方面包括开发和/或复制。
Covance can provide inhalation toxicology services for a broad range of safety assessments, be they standard studies or novel ones requiring innovative approaches and unique delivery devices.
Benefit from Covance’s expertise and innovative approaches in inhalation toxicology
- 40多年的经验进行吸入研究，以认可全球标准，标准化学品，难以处理和危险的材料，包括纳米材料。
- A reputation for innovating in both study design and delivery mechanisms to optimize inhalation toxicology study success.
- 专门的吸入毒理学专家，包括气溶胶技术人员，专业动物技术人员，工程师，病理学家通过吸入科学毒理学专家领导。
Your Needs
吸入毒理学研究可以提供独特而复杂的挑战
Planning and managing any toxicology study can be daunting; however, inhalation toxicology studies pose unique challenges and complexities. You need to tailor studies to your chemical and optimize them for physiochemical properties and the required regulatory endpoints. You may need to refine standard test approaches to ensure study integrity. This means partnering with a team you can trust to design and manage your inhalation toxicology studies in a way that is right for you and your chemical.
我们的能力
An inhalation toxicology team with extensive and diverse expertise
Covance吸入毒理学团队由各种背景的一系列专家组成，并在规划和运行吸入毒理学研究方面拥有丰富的经验。该团队包括工程师，气溶胶技术专家，动物福利专家，Vets，化学分析师，病理学家和吸入科学毒理学专家。
Performing recognized inhalation studies to deliver reliable results
Covance在进行常见吸入毒理学研究方面具有以下内容，如：
- 对致癌性急性致癌性
- 有氧运动toxicity to assessing anesthetic potential
- 用特定方法和多达24小时/天的研究
- Embryofetal to two-generation reproductive studies
Innovating to address your specific challenges and optimize results
有时标准方法不起作用 - 这是我们的“首先”吸入毒理学心态，可以帮助设计适合您独特挑战的解决方案。这可能是解决异常端点或在使用非标准的动物物种时。或者，它可能意味着定制吸入输送设备以优化数据质量。这可以通过定制的吸入室甚至通过特定于各个测试动物的3D打印面罩。作为您的伴侣，Covance可以创新和提高标准的研究方法，以优化它们的化学品。
Utilizing state-of-the-art analytical techniques and facilities to produce high-quality data
与分析科学家携手合作，吸入毒理学团队确保了高质量的数据以适当的时间表生产。使用的分析方法包括GC，IR，UPLC和HPLC分析和化合物特异性分析。
为广泛的常见和罕见的物种提供高福利标准
Covance is proud of the high welfare standards observed in all our in vivo work and especially in inhalation studies where a broad range of common and uncommon species may be required. An expert team of animal technicians and veterinarians conduct in vivo studies to ensure the highest levels of animal care. Inhalation studies can be performed on the following species:
- Mouse
- 兔子
- 狗
- MINIPIG.
- Pygmy goat
- 牛