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Histopathological assessments: Ocular
Pathology, Toxicology, Anatomic Pathology, Ocular tox
透射电子显微镜(TEM)和服务reporting
Transmission electron microscopy (TEM) is a microscopy technique that can produce very high magnification and resolution images compared to standard light microscopy.
TEM uses electrons instead of light as a radiation source and involves passing an electron beam through an ultra-thin section of the specimen giving rise to black and white, two-dimensional cross-section images.
TEM is useful for investigating the structure of macromolecular complexes, organelles, cells and tissues, and is used in preclinical safety evaluation and mechanistic studies where visualization of subcellular structures can be used to determine functional changes and give information relevant to other safety endpoints.
About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC.Learn more about our commitment to replacing, reusing and refining nonclinical research models.