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有毒ity study: Embryo-fetal developmental
DART
Fetal pathological evaluations (outsourced)
Record Type:Technique
Validation:GLP,Non-GLP
Models:Mouse,老鼠,Guinea Pig,Hamster,Rabbit,Canine,NHP
Disease:Reproductive Health
If you're looking to outsource non-regulatory, investigative work or need a large GLP or GCP compliant fetal pathology exam as a complement to your existing studies, you can order fetal pathology evaluations as standalone contract work.
Embryo-fetal development studies are usually performed on a rodent and rabbit and the fetuses from the treated dams are examined for developmental and structural abnormalities by soft tissue techniques e.g., modified Wilson Technique (for head and whole body) and for skeletal and cartilage examination techniques e.g., modified Dawson Technique (single-stained Alizarin Red or double-stained in combination with Alizarin Blue.)
Processing and staining procedures can be included on request, and a fetal pathology phase report is included upon exam completion.
Related Capabilities
About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC.Learn more about our commitment to replacing, reusing and refining nonclinical research models.