OECD 413 / OCSPP 870.3465是一项验证测试，旨在通过在重复暴露后进行90天的吸入来表征化学毒性，通常用于提供定量吸入风险评估的数据。至少10只雄性啮齿动物的组至少在三个或更多浓度水平下暴露于测试化学品，每天六小时为90天;将其与过滤空气（负控制）和/或车辆（车辆控制）进行比较。

Animals can be exposed for five or seven days per week. Males and females are always tested, but they may be exposed at different concentration levels if it is known that one sex is more susceptible to a given test chemical. The results of the study can provide information including hematology, clinical chemistry, ophthalmology, gross pathology, organ weights, and histopathology, to help better characterize the toxicity of a test chemical.