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oppts 870.7600：真皮渗透
Metabolism
体内药代动力学（PK）
Pharmacokinetics (PK) tests are carried out to understand an API’s effectiveness and safety.
The assays investigate the API’s absorption, biodistribution, metabolism and excretion, which can help identify the appropriate dose and distribution.
评估动物模型中的体内药代动力学，如啮齿动物物种和NHP，揭示了API与体内的相互作用，以及功效的强度和持续时间。
Data from PK assays also help select dosage for preclinical and clinical studies. This test uses Phoenix WinNonlin for data processing and reporting.
About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC.了解有关我们对更换，重新塑造和炼制非临床研究模式的承诺。