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EPPND和EFD NHP研究
自国际委员会释放技术要求（ICH）指南S6（R1）2011年前后发育（PPND）和胚胎发育（EFD）毒性研究，已经可以在a中进行两项研究类型单一研究叫做增强了前后发展（EPPND）。
Especially for molecules where NHP models have been the only acceptable model, the ePPND study design has led to a greater reduction in research models. Furthermore, the new guideline also postponed the study performance into the late phase of clinical trials (Phase III), further reducing the number of nonclinical models needed since fewer molecules make it to this late stage in drug development.
主要是大分子（抗体或同样的生物发作）的测试制品是NHP EPPND研究的重点，由于它们的高度特异性靶标，这些研究仅在与人类密切相关的物种中被发现。
About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC.了解有关我们对更换，重新塑造和炼制非临床研究模式的承诺。